Place pan in refrigerator to cool as you begin. Begin with Jello; mix 1 package Jello with 1 envelope Knox and 1 cup boiling water. Let cool a bit then pour into chilled pan; refrigerate until well set (takes approximately 10 minutes). Prepare milk, 1 cup boiling water, and 2 envelopes Knox mixed with canned milk.
Pour 3/4 cup of milk over first layer of Jello. Refrigerate until set, about 10 minutes. While waiting, prepare another color (or 2) of Jello. Alternate milk and Jellos, 4 layers of Jello and 3 layers of milk.