Cook ziti according to directions; drain. Saute chopped meat with onion; drain. Mix ziti with meat/onion mixture.
Meanwhile, beat egg; mix with oregano and garlic powder. Mix this mixture with Ricotta, wine and sauce. Turn ziti/meat mixture into a baking pan with ricotta/sauce mix; mix well. Top with sliced Mozzarella. Bake at 350 degrees for approximately one hour.