Preheat oven and baking sheet to 350 degrees. In a small bowl, combine cream cheese, 1/4 cup sugar, vanilla and egg. Beat until smooth and creamy. Spread on unbaked pie crust.
In a medium bowl, combine pumpkin, 1/3 cup sugar, spices and salt. Add milk and eggs; mix well. Pour over cream cheese mixture. Bake on preheated baking sheet for 50-55 minutes or until puffy and sets. Cool on a wire rack. Makes one 9 inch pie.